Physiologic consequences of pneumonectomy

Physiologic consequences and complications of vasectomy.

Sterilization of men and women is the most popular method of contraception in Canada. The contraceptive effect of a vasectomy usually occurs within 3 months. The production of sperm, however, is not interrupted, and an increase in pressure proximal to the ligation site may cause rupture of the epididymis or the ductus deferens, with extravasation of spermatozoa and the formation of granulomas o...

Biochemical and physiologic consequences of boron deprivation in humans.

Boron deprivation experiments with humans have yielded some persuasive findings for the hypothesis that boron is an essential nutrient. In the first nutritional study with humans involving boron, 12 postmenopausal women first were fed a diet that provided 0.25 mg boron/2000 kcal for 119 days, and then were fed the same diet with a boron supplement of 3 mg boron/day for 48 days. The boron supple...

Physiologic and molecular consequences of endothelial Bmpr2 mutation

BACKGROUND Pulmonary arterial hypertension (PAH) is thought to be driven by dysfunction of pulmonary vascular microendothelial cells (PMVEC). Most hereditary PAH is associated with BMPR2 mutations. However, the physiologic and molecular consequences of expression of BMPR2 mutations in PMVEC are unknown. METHODS In vivo experiments were performed on adult mice with conditional endothelial-spec...

Antipyretic therapy: physiologic rationale, diagnostic implications, and clinical consequences.

Various treatments have been used to suppress fever since antiquity. Surprisingly, few studies have been performed to ascertain the physiologic consequences of antipyresis and validate the rationale behind such therapy. More importantly, it has not been established conclusively that the benefits of antipyretic therapy outweigh its risks. The present review considers these issues in light of cur...

A new physiologic race